Mito Energy (MOTS-C)
Mito Energy is Better Med Spa’s MOTS‑C peptide program, designed to enhance mitochondrial function, exercise capacity, insulin sensitivity, and visceral fat metabolism in high‑output clients. Delivered as a structured, non‑FDA–approved protocol with informed consent, it includes baseline labs, dosing guidance, and integration with nutrition, training, and recovery services.
How It Works
MOTS‑C is a short peptide encoded in mitochondrial DNA that behaves as an “exercise signal,” activating AMPK and related stress‑response pathways to boost mitochondrial biogenesis, fatty‑acid oxidation, and glucose uptake in preclinical studies. Animal and early human research suggests it can improve endurance, enhance insulin sensitivity, reduce diet‑induced obesity and fatty liver, and help muscles adapt to metabolic stress. At Better Med Spa, MOTS‑C is used off‑label under a non‑FDA waiver with conservative dosing, careful screening, and ongoing monitoring to align potential benefits with safety and client goals.
What It Targets
Our MOTS-C peptides are designed to target:
- Low energy and “metabolic drag” in active clients who still feel sluggish despite clean nutrition and training.
- Insulin resistance, carb intolerance, or stubborn midsection fat tied to impaired mitochondrial and metabolic function.
- Performance plateaus where clients want better work capacity, recovery, and adaptation to training.
- Visceral fat and cardiometabolic risk patterns in clients who are already focused on lifestyle and, when appropriate, other metabolic therapies.
Benefits
MOTS-C is believed to help with:
- Supports mitochondrial function and cellular energy pathways associated with improved exercise capacity and fatigue resistance in preclinical studies.
- Enhances insulin sensitivity and glucose utilization in animal and early mechanistic studies, which may help with carb tolerance and body composition when combined with diet and movement.
- May reduce visceral fat and fatty liver markers in research settings, suggesting potential benefit for long-term cardiometabolic health.
- Offered as part of a structured, non‑FDA–approved protocol with informed consent, diagnostics, and integration into Better Med Spa’s performance, GLP‑1, and body-contouring ecosystems for a 360° approach.
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Questions?
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What is MOTS‑C and why is it used in Mito Energy?
MOTS‑C is a mitochondrial‑derived peptide that acts as a stress‑response signal, turning on AMPK and other pathways that support mitochondrial biogenesis, fat oxidation, and glucose handling. In Mito Energy, it is used off‑label under a non‑FDA waiver for high‑performing clients who want advanced support for energy, metabolism, and exercise adaptation alongside foundational wellness habits.
Is MOTS‑C FDA‑approved?
No. MOTS‑C is not FDA‑approved for any indication, and its status as a bulk drug substance has raised safety and regulatory questions, including potential immunogenicity and impurity concerns. Better Med Spa only offers MOTS‑C under a non‑FDA–approved informed consent model that clearly explains its experimental nature, data gaps, and alternative options.
Who is a good candidate for Mito Energy?
Candidates are typically active, wellness‑focused adults with fatigue, metabolic sluggishness, or stubborn visceral fat who already commit to nutrition, training, and sleep and are comfortable with a research‑aligned, non‑FDA modality. Each client undergoes a thorough intake, labs, and risk–benefit discussion before being considered for MOTS‑C.
What are the risks or unknowns?
Preclinical and early data suggest MOTS‑C is generally well tolerated, but long‑term safety and immune responses are not fully understood. Better Med Spa uses conservative dosing, excludes high‑risk populations (such as active malignancy), and requires regular follow‑up for continued use.
How does Mito Energy integrate with other Better Med Spa services?
Mito Energy is usually layered onto performance, GLP‑1, or Tesamorelin programs and paired with IV therapy, body-contouring, and K‑Beauty facials to align cellular energy and metabolic health with visible body and skin changes. Many clients choose membership or package structures that combine peptides, labs, coaching, and aesthetic services with automated follow-ups to track energy, composition, and recovery over time.