Mito Energy (MOTS-C)
Lincoln Park, Chicago

Starting at $400

Mito Energy is Better Med Spa’s MOTS‑C peptide program, designed to enhance mitochondrial function, exercise capacity, insulin sensitivity, and visceral fat metabolism in high‑output clients. Delivered as a structured, non‑FDA–approved protocol with informed consent, it includes baseline labs, dosing guidance, and integration with nutrition, training, and recovery services.

Questions?

We're here to answer your questions and provide the best services for your needs.

What is MOTS‑C and why is it used in Mito Energy?

MOTS‑C is a mitochondrial‑derived peptide that acts as a stress‑response signal, turning on AMPK and other pathways that support mitochondrial biogenesis, fat oxidation, and glucose handling. In Mito Energy, it is used off‑label under a non‑FDA waiver for high‑performing clients who want advanced support for energy, metabolism, and exercise adaptation alongside foundational wellness habits.

Is MOTS‑C FDA‑approved?

No. MOTS‑C is not FDA‑approved for any indication, and its status as a bulk drug substance has raised safety and regulatory questions, including potential immunogenicity and impurity concerns. Better Med Spa only offers MOTS‑C under a non‑FDA–approved informed consent model that clearly explains its experimental nature, data gaps, and alternative options.

Who is a good candidate for Mito Energy?

Candidates are typically active, wellness‑focused adults with fatigue, metabolic sluggishness, or stubborn visceral fat who already commit to nutrition, training, and sleep and are comfortable with a research‑aligned, non‑FDA modality. Each client undergoes a thorough intake, labs, and risk–benefit discussion before being considered for MOTS‑C.

What are the risks or unknowns?

Preclinical and early data suggest MOTS‑C is generally well tolerated, but long‑term safety and immune responses are not fully understood. Better Med Spa uses conservative dosing, excludes high‑risk populations (such as active malignancy), and requires regular follow‑up for continued use.

How does Mito Energy integrate with other Better Med Spa services?

Mito Energy is usually layered onto performance, GLP‑1, or Tesamorelin programs and paired with IV therapy, body-contouring, and K‑Beauty facials to align cellular energy and metabolic health with visible body and skin changes. Many clients choose membership or package structures that combine peptides, labs, coaching, and aesthetic services with automated follow-ups to track energy, composition, and recovery over time.

How It Works

MOTS‑C is a short peptide encoded in mitochondrial DNA that behaves as an “exercise signal,” activating AMPK and related stress‑response pathways to boost mitochondrial biogenesis, fatty‑acid oxidation, and glucose uptake in preclinical studies. Animal and early human research suggests it can improve endurance, enhance insulin sensitivity, reduce diet‑induced obesity and fatty liver, and help muscles adapt to metabolic stress. At Better Med Spa, MOTS‑C is used off‑label under a non‑FDA waiver with conservative dosing, careful screening, and ongoing monitoring to align potential benefits with safety and client goals.

What It Targets

Our MOTS-C peptides are designed to target:

  • Low energy and “metabolic drag” in active clients who still feel sluggish despite clean nutrition and training.​
  • Insulin resistance, carb intolerance, or stubborn midsection fat tied to impaired mitochondrial and metabolic function.​
  • Performance plateaus where clients want better work capacity, recovery, and adaptation to training.​
  • Visceral fat and cardiometabolic risk patterns in clients who are already focused on lifestyle and, when appropriate, other metabolic therapies.

Benefits

MOTS-C is believed to help with:

  • Supports mitochondrial function and cellular energy pathways associated with improved exercise capacity and fatigue resistance in preclinical studies.
  • Enhances insulin sensitivity and glucose utilization in animal and early mechanistic studies, which may help with carb tolerance and body composition when combined with diet and movement.
  • May reduce visceral fat and fatty liver markers in research settings, suggesting potential benefit for long-term cardiometabolic health.
  • Offered as part of a structured, non‑FDA–approved protocol with informed consent, diagnostics, and integration into Better Med Spa’s performance, GLP‑1, and body-contouring ecosystems for a 360° approach.
Your Treatment

Experience the best in aesthetic and wellness care at Better Med Spa. Our personalized treatments are tailored to you, designed to help you look and feel your absolute best with confidence and ease.

Better Med Spa hours
Mon, Tues, Wed, Thurs:
10:00 AM - 7:00 PM
Fri, Sat, Sun:
9:00 AM - 5:00 PM

Past Client Experiences

"I have noticed a significant difference in the overall appearance of my skin and my friends and family have as well. I am excited to come in for follow-up sessions!"

"I came in 2 weeks ago for their Green Peel, which is a natural facial peel formulated with algae. It was my first time doing a skin peel so I was a bit anxious, but my tech Priscilla did a great job of informing me about the treatment throughout the process and about the aftercare."

Signature from Kat Z.
Chicago, IL

"Overall - phenomenal experience. Staff from the estheticians to the front desk were so knowledgeable and kind."

"I got the Personalized Facial with a complimentary skin consultation with Xia. And it was so beyond amazing. This was by far one of the most intensive facials that I have ever gotten and I loved how much attention to detail Xia had throughout our entire session."

Signature from Annie Y.
Austin, TX

"Outstanding service and spa."

"The Glass Facial was amazing. They specialize in Korean Beauty and only use products gentle for your skin unlike many Western treatments. My skin looks great even days later. I still have a glow and glass look with just simple skin care and moisturizing like I normally do. I definitely recommend this salon and suggest you try the K-Beauty services!"

Signature from Ashley R.
Chicago, IL

"This is definitely a place I trust and will keep coming back to for my future skincare treatments. Plus, reasonable price! Highly recommended!"

"It has been a month since I got Rejuran, and at least six people have complimented my skin since then! Izzy is amazing, her technique is professional and surprisingly painless, but what impressed me the most is her sense of aesthetics. She really listened to what I wanted, communicated actively with me, and confirmed everything carefully until I felt completely comfortable."

Signature from Yuxin Z.
Chicago, IL

"The spa was clean, relaxing, and welcoming. My skin feels so smooth and fresh, and I left glowing."

"I had my very first facial today with Hailey and it was such a great experience! I booked the aromatherapy, dermaplaning, glass skin facial, and LED light treatment, and she walked me through every step so I felt comfortable the whole time. She made sure I was comfortable and explained what each product was doing. I’ll definitely be coming back and recommending this place to friends!"

Signature from Gabrielle B.
Chicago, IL

"I am so grateful that I did my facial treatment at Better Med Spa, the place is very cozy and they are all professional with a warm personality."

"I had my facial treatment with Hailey. She provided me with comprehensive information about facial and its effects on my skin. I’m so happy, satisfied and delighted with the result. Her kindness and outstanding professionalism are truly INCREDIBLE."

Signature from Loreme R.
Chicago, IL

"From the moment I walked in, the atmosphere was welcoming and relaxing. I noticed an immediate glow to my skin and am excited to see the long-term results as my skin continues to heal. Highly recommend!"

"My esthetician was incredibly nice and took the time to explain the entire process to me, which really put me at ease. I appreciated how she tailored the treatment to my skin's needs, ensuring I received the best possible results. After the session, she provided me with thorough aftercare instructions, which I found very helpful."

Signature from Cindy T.
Chicago, IL

"I went in with no clear expectations because it isn't something that I've ever done before. I will definitely be doing it again every time I'm in Chicago for another visit."

"Grace did a fantastic job. I don't have anything to compare it with, but the full service felt amazing. I was surprised by the number of steps included and how involved it ended up being. Head massage, facial massage, neck and shoulder massage, forearm and hand massage, all while working through multiple steps of the facial cleanse and treatment process. It was great. I'll be back again."

Signature from Jacob B.
Chicago, IL

"Loved my experience at Better Med Spa! Super friendly, very informative, and excellent at what they do."

"Went in for microneedling and EZ Gel. I felt confident and comfortable the whole time. Highly recommend!"



Signature from Jocelyn M.
Chicago, IL

"I absolutely look forward to coming here every month to get service by the wonderful ladies who work at this spa."

"The results are truly unbelievable and I’m left speechless each time I leave. I would highly recommend buying a membership it helps you pour into yourself monthly and the results and satisfaction won’t disappoint!"

Signature from Rochaela B.
Chicago, IL