Rejuran is a Salmon DNA-based treatment that rejuvenates skin by repairing, hydrating, and boosting collagen at our Chicago med spa in Lincoln Park.
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Discover why Rejuran, the Korean “Salmon DNA skin healer,” is one of the most sought-after skin rejuvenation treatments in the U.S., now available at Better Med Spa in Lincoln Park, Chicago. This thorough guide explains everything you need to know - from the science behind the treatment and its benefits to what to expect during sessions and how it fits into the busy Chicago lifestyle.
Rejuran is an advanced skin rejuvenation treatment that uses purified DNA fragments called polynucleotides (PN), extracted from salmon sperm. These polynucleotides are structurally similar to human DNA, making them highly biocompatible and safe for almost all skin types, including those with seafood allergies because of a proprietary purification process called DNA Optimising Technology (DOT).
Unlike traditional dermal fillers that focus on volume restoration, Rejuran targets skin healing on a cellular level. It stimulates the skin’s natural repair mechanisms by encouraging cell regeneration, boosting collagen and elastin production, reducing inflammation, and repairing damaged tissue.
Originating in South Korea, a global leader in innovative skincare (K-beauty), Rejuran has gained rapid popularity internationally, praised for delivering natural-looking results with minimal downtime.
The polynucleotides in Rejuran are short DNA fragments that prompt various restorative effects when injected into the dermis. This includes:
By working at this foundational level, Rejuran supports healthier, more resilient skin that ages gracefully and recovers quicker from damage.
Rejuran is suitable for a wide range of skin concerns and types, especially for those looking to address:
Because Rejuran works to improve skin from inside out, it's a favorite for patients who want to age gracefully or strengthen their skin foundation in preparation for future treatments.
At Better Med Spa in Lincoln Park, every Rejuran journey begins with a comprehensive, personalized skin consultation. Our experienced estheticians assess your skin concerns, history, and goals to tailor the treatment best suited for you.
Rejuran effects are gradual and cumulative. You'll notice enhanced hydration and smoother skin texture within 7 days, with firmer, younger-looking skin continuing to develop over 4-6 weeks. Most clients benefit from a series of 3-4 treatments spaced about 4 weeks apart.
This combination of benefits makes Rejuran especially suited for Chicagoans who face skincare challenges due to city living and climate.
Rejuran's primary action is aiding cellular regeneration and providing a collagen boost. The product is sourced from purified salmon DNA (polynucleotides) and is reported to provide a cumulative effect of building natural skin rejuvenation. Typical treatments provide full absorption, leaving no residue, and the service is described as suitable for sensitive skin due to the highly purified nature of the product. Clients typical seek Rejuran to address skin texture, elasticity, and fine lines.
Hyaluronic acid fillers typically come up when researching Rejuran - the difference is that hyaluronic acid fillers target volume restoration for those looking to address volume loss or wrinkle reduction. Hyaluronic acid fillers are derived from synthetic or natural HA gels, and they result in immediate volume that lasts for a short-to-medium term period. These treatments also carry a potential for allergies or swelling for those with sensitive skin, but they are often highlighted for leaving patients with little-to-no swelling or downtime.
PRP (Platelet-Rich Plasma) is another service that may come up in research alongside Rejuran, though it is a different and unique process that promotes skin healing and texture improvement by utilizing the patient's own blood components (plasma) to promote gradual healing. There is minimal downtime involved in PRP, but quality depends on individual health.
Rejuran is valued for its unique approach: supporting deep skin health and resilience rather than just filling or simply stimulating collagen superficially.
To get the best results from your Rejuran session:
You may notice:
Rejuran also pairs well with other med spa treatments like microneedling, laser resurfacing, or chemical peels to enhance and prolong skin rejuvenation.
At Better Med Spa in Lincoln Park, we understand Chicago’s unique skin challenges - from harsh winters with dry, cold air to hot, humid summers and constant exposure to pollution. These factors accelerate skin aging and sensitivity.
Rejuran’s regenerative properties help counteract these effects by replenishing the skin’s natural defenses and repair capability. Our clients love how it leaves their skin glowing, hydrated, and visibly healthier - a perfect fit for anyone balancing an active urban lifestyle with skin wellness goals.
Is Rejuran painful?
The injections use fine needles with topical numbing, and most clients report minimal discomfort.
Can I have Rejuran if I have sensitive or allergy-prone skin?
Yes. The purified salmon DNA used is hypoallergenic and safe for sensitive skin, including those with seafood allergies.
When will I see results?
Noticeable improvements begin around 7 days, with optimal results after 3-4 monthly sessions.
Are there any side effects?
Temporary redness, swelling, or bruising may occur but typically resolve quickly.
Can men also get Rejuran?
Absolutely. Rejuran is popular with all genders who want subtle, natural skin rejuvenation.
If you’re ready to rejuvenate your skin with the power of Salmon DNA, Better Med Spa in Lincoln Park is your trusted Chicago destination. Our expert team personalizes every treatment to your unique skin needs, helping you achieve a radiant, youthful complexion without surgery or harsh interventions.
Schedule your consultation today and discover how Rejuran can help you glow from the inside out - perfectly suited for Chicago’s North Side lifestyle.