Rejuran Treatment Chicago: The Ultimate Guide to Salmon DNA Skin Rejuvenation at Better Med Spa

Discover why Rejuran, the Korean “Salmon DNA skin healer,” is one of the most sought-after skin rejuvenation treatments in the U.S., now available at Better Med Spa in Lincoln Park, Chicago. This thorough guide explains everything you need to know - from the science behind the treatment and its benefits to what to expect during sessions and how it fits into the busy Chicago lifestyle.

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What Is Rejuran? An Introduction to Salmon DNA Skin Therapy

Rejuran is an advanced skin rejuvenation treatment that uses purified DNA fragments called polynucleotides (PN), extracted from salmon sperm. These polynucleotides are structurally similar to human DNA, making them highly biocompatible and safe for almost all skin types, including those with seafood allergies because of a proprietary purification process called DNA Optimising Technology (DOT).​

Unlike traditional dermal fillers that focus on volume restoration, Rejuran targets skin healing on a cellular level. It stimulates the skin’s natural repair mechanisms by encouraging cell regeneration, boosting collagen and elastin production, reducing inflammation, and repairing damaged tissue.​

Originating in South Korea, a global leader in innovative skincare (K-beauty), Rejuran has gained rapid popularity internationally, praised for delivering natural-looking results with minimal downtime. Recognized as the number one skin booster in South Korea, a country renowned for setting global trends in advanced skin science, Rejuran’s rise is fueled by both its impressive efficacy and the discerning standards of Korean consumers, who are quick to embrace breakthroughs that deliver on their promises.

South Korea’s skincare landscape is constantly evolving, with experts and beauty enthusiasts alike moving swiftly from trends like exosome-based treatments to polynucleotide-based therapies such as Rejuran for their superior regenerative power. This enthusiasm for innovation has helped Rejuran and its unique polynucleotide (PN) technology become a staple in K-beauty regimens, making its way into med spas around the world. The treatment’s embrace by trendsetters and skin professionals reflects not just its roots in cutting-edge Korean research, but also its proven ability to rejuvenate skin at a cellular level for visibly smoother, healthier, and more resilient skin.

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How Does Rejuran Work? The Science Behind the Salmon DNA

The polynucleotides in Rejuran are short DNA fragments that prompt various restorative effects when injected into the dermis. This includes:​

• Cellular regeneration: Encourages skin cells to repair micro-damage and accelerate turnover.​
• Collagen stimulation: Increases synthesis of collagen types I and III, essential proteins for structural support and elasticity.​
• Anti-inflammatory action: Reduces oxidative stress and calms skin irritations, making it beneficial for sensitive or inflamed skin.​
• Angiogenesis: Promotes formation of new blood vessels, enhancing skin tone, elasticity, and hydration.​
• Barrier restoration: Strengthens the skin’s protective outer layer to retain moisture and shield against environmental stressors.

By working at this foundational level, Rejuran supports healthier, more resilient skin that ages gracefully and recovers quicker from damage.

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What Does PDRN (Polydeoxyribonucleotide) Do for Your Skin?

At the heart of Rejuran’s effectiveness lies PDRN, a naturally-derived DNA fragment that acts as a cellular communicator. Once introduced to the skin, PDRN essentially instructs your cells to kickstart their repair processes. This means more rapid skin rejuvenation and visible improvements in strength, texture, and elasticity.

Here’s how PDRN enhances skin vitality:

• Stimulates growth and healing: By signaling skin cells (fibroblasts) to ramp up production, PDRN helps repair micro-damage from aging, sun, or pollution.
• Accelerates cell turnover: New, healthy cells surface faster, leading to a brighter, smoother complexion.
• Boosts collagen and elastin synthesis: Essential for firm, resilient skin, these proteins are produced in greater quantities, reducing fine lines and restoring youthful plumpness.
• Balances inflammation: PDRN’s calming action helps soothe redness or irritation, making it ideal for sensitive or post-procedure skin.

By directly targeting the underlying foundation of your skin, PDRN ensures true regeneration - offering both immediate radiance and lasting resilience.

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Who Can Benefit? Ideal Candidates for Rejuran in Chicago

Rejuran is suitable for a wide range of skin concerns and types, especially for those looking to address:

• Early signs of aging such as fine lines and loss of elasticity.​
• Dull, rough, or uneven skin texture caused by urban pollution and seasonal changes typical in Chicago.​
• Sensitive or inflamed skin, including those with rosacea or redness post-procedures.​
• Acne scars, enlarged pores, and post-treatment recovery (e.g., after lasers or microneedling).​
• Anyone wanting a natural, subtle rejuvenation without the look or feel of traditional fillers.​

Because Rejuran works to improve skin from inside out, it's a favorite for patients who want to age gracefully or strengthen their skin foundation in preparation for future treatments.

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What Happens During a Rejuran Treatment at Better Med Spa?

At Better Med Spa in Lincoln Park, every Rejuran journey begins with a comprehensive, personalized skin consultation. Our experienced estheticians assess your skin concerns, history, and goals to tailor the treatment best suited for you.

Treatment Procedure

1. Preparation: The skin is cleansed thoroughly. A topical numbing cream is applied to ensure your comfort during injections.​
2. Microinjections: Using a fine needle, the Rejuran solution is carefully injected into targeted areas of the face or neck where skin repair is needed. Common zones include cheeks, under-eyes, forehead, and jawline.​
3. Duration: The session typically takes 30-60 minutes depending on areas treated.​
4. Aftercare: Minimal downtime is involved. You may experience mild redness, swelling, or pinpoint bruising for 1-2 days. Our team provides detailed aftercare instructions to maximize results.​

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Treatment Series for Best Results

Rejuran effects are gradual and cumulative. You'll notice enhanced hydration and smoother skin texture within 7 days, with firmer, younger-looking skin continuing to develop over 4-6 weeks. Most clients benefit from a series of 3-4 treatments spaced about 4 weeks apart.​

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Benefits of Rejuran: Why Chicago Clients Love It

• Deep skin repair: Reverses microscopic damage from urban pollution and lifestyle stressors in Chicago.​
• Boosts collagen naturally: Firms and lifts skin without artificial filler effects.​
• Improves elasticity: Makes skin more supple and resilient to environmental factors like wind, cold, and humidity swings.
• Reduces fine lines and wrinkles: Smooths early aging signs gently yet effectively.
• Hydrates and soothes: Ideal for sensitive skin prone to redness or irritation, common especially during Chicago seasonal changes.​
• Shrinks pores and fades acne scars: Enhances overall smoothness and clarity.
• No permanent residues: The salmon DNA is fully absorbed, leaving no fillers or unnatural materials behind.​
• Safe for nearly all skin types and ages: Even those with allergies or sensitive skin can benefit safely.

This combination of benefits makes Rejuran especially suited for Chicagoans who face skincare challenges due to city living and climate.

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Rejuran vs. Other Injectable Treatments

Rejuran's primary action is aiding cellular regeneration and providing a collagen boost. The product is sourced from purified salmon DNA (polynucleotides) and is reported to provide a cumulative effect of building natural skin rejuvenation. Typical treatments provide full absorption, leaving no residue, and the service is described as suitable for sensitive skin due to the highly purified nature of the product. Clients typical seek Rejuran to address skin texture, elasticity, and fine lines.

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Hyaluronic acid fillers typically come up when researching Rejuran - the difference is that hyaluronic acid fillers target volume restoration for those looking to address volume loss or wrinkle reduction. Hyaluronic acid fillers are derived from synthetic or natural HA gels, and they result in immediate volume that lasts for a short-to-medium term period. These treatments also carry a potential for allergies or swelling for those with sensitive skin, but they are often highlighted for leaving patients with little-to-no swelling or downtime.

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PRP (Platelet-Rich Plasma) is another service that may come up in research alongside Rejuran, though it is a different and unique process that promotes skin healing and texture improvement by utilizing the patient's own blood components (plasma) to promote gradual healing. There is minimal downtime involved in PRP, but quality depends on individual health.

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Rejuran is valued for its unique approach: supporting deep skin health and resilience rather than just filling or simply stimulating collagen superficially.

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Comparing Rejuran with Exosome-Based Treatments

As advanced skin rejuvenation continues to evolve, exosome-based therapies have recently caught the spotlight, internationally and especially within skincare circles that keep pace with emerging science. Exosomes, tiny vesicles found in cells, carry growth factors and signaling molecules that help facilitate skin repair and regeneration. Treatments utilizing exosomes seek to harness these benefits by encouraging cellular communication, aiming for revitalized, healthier-looking skin.

However, when we look at the current preferences among discerning skincare clients and practitioners, particularly in South Korea where skincare advancements often originate, there's a noticeable shift toward polynucleotide (PDRN) therapies like Rejuran. The key factor? While exosome therapies focus primarily on surface-level cellular communication, PDRN-based treatments such as Rejuran deliver deeper skin repair by stimulating cellular regeneration at the foundational level. This lends Rejuran an edge for those interested in supporting long-term resilience and natural skin renewal, not just surface improvement.

In summary:

• Exosome treatments: Aim for brighter, revitalized skin by enhancing cell-to-cell communication.
• Rejuran (PDRN products): Support profound, lasting changes by building skin health and structure from within.

For clients weighing these options, the choice often comes down to whether the priority is a quick, radiance-boosting fix or investing in deeper skin resilience and regeneration.

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Preparing for Your Rejuran Treatment in Lincoln Park

To get the best results from your Rejuran session:

• Avoid alcohol, aspirin, and blood thinners 3-5 days before treatment to reduce bruising risk.​
• Arrive with a clean, makeup-free face for smooth injection.​
• Discuss your full medical and allergy history during your consultation for maximum safety.
• Follow post-treatment care recommendations, including avoiding heavy exercise, saunas, or direct sun exposure for a few days.​

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Post-Treatment Care and Expected Results

You may notice:

• Mild swelling or redness for 1-2 days. Using a cold compress and avoiding touching the face helps ease symptoms.​
• Initial hydration and brightness within a week.
• Improved texture, smoothness, and firmness appearing over 4-6 weeks as collagen rebuilds.​
• Long-lasting effects with maintenance treatments approximately every 6-12 months.

Rejuran also pairs well with other med spa treatments like microneedling, laser resurfacing, or chemical peels to enhance and prolong skin rejuvenation.​

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Rejuran in Chicago: Local Insight

At Better Med Spa in Lincoln Park, we understand Chicago’s unique skin challenges - from harsh winters with dry, cold air to hot, humid summers and constant exposure to pollution. These factors accelerate skin aging and sensitivity.

Rejuran also pairs well with other med spa treatments like microneedling, laser resurfacing, or chemical peels to enhance and prolong skin rejuvenation.​ In fact, it can be applied during or after procedures such as RF microneedling, traditional microneedling, or laser treatments to further boost healing, improve results, and speed up recovery time. This synergy means you can enjoy smoother, brighter, and more resilient skin, often with less downtime, when combining Rejuran with these popular skin therapies.

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Frequently Asked Questions About Rejuran

Is Rejuran painful?
The injections use fine needles with topical numbing, and most clients report minimal discomfort.​

Can I have Rejuran if I have sensitive or allergy-prone skin?
Yes. The purified salmon DNA used is hypoallergenic and safe for sensitive skin, including those with seafood allergies.​

When will I see results?
Noticeable improvements begin around 7 days, with optimal results after 3-4 monthly sessions.​

Are there any side effects?
Temporary redness, swelling, or bruising may occur but typically resolve quickly.​

Can men also get Rejuran?
Absolutely. Rejuran is popular with all genders who want subtle, natural skin rejuvenation.​

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Booking Your Rejuran Experience at Better Med Spa & Wellness

If you’re ready to rejuvenate your skin with the power of Salmon DNA, Better Med Spa in Lincoln Park is your trusted Chicago destination. Our expert team personalizes every treatment to your unique skin needs, helping you achieve a radiant, youthful complexion without surgery or harsh interventions.

Schedule your consultation today and discover how Rejuran can help you glow from the inside out - perfectly suited for Chicago’s North Side lifestyle.

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The content provided on this blog is for educational purposes only and does not substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of your healthcare provider for any questions regarding your health or medical conditions. We strive to present accurate and up-to-date information, but outcomes and experiences may vary. Our med spa is not responsible for any actions taken based on this blog. If treatments, products, or procedures are mentioned, please consult with a licensed professional to determine if they are appropriate for you.