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The Executive Longevity Panel is a 22-panel blood draw designed for patients who think about their health in decades, not months. It builds on the full hormonal, thyroid, metabolic, and nutritional scope of our Elite Performance Optimization Panel and adds three markers that longevity medicine has identified as critical and that standard bloodwork never includes: Apolipoprotein B (a superior predictor of cardiovascular events vs. LDL cholesterol), Lipoprotein(a) (a genetically determined cardiovascular risk factor most physicians never test), and homocysteine (a cardiovascular and neurological risk marker tied to B-vitamin metabolism). A second inflammatory marker (ESR) rounds out the panel for a dual-axis view of systemic inflammation.
This panel targets seven clinical domains: full thyroid with autoimmune markers, sex hormones with SHBG, adrenal stress response, metabolic and insulin health, advanced cardiovascular risk (Apo-B, Lp(a), homocysteine), dual inflammatory assessment (hs-CRP and ESR), and nutritional status. It is designed for patients who want the longevity-grade data that informs decisions about how they age over the next 20 years.
An 8-to-12-hour fast is required. The blood draw takes about 10 minutes at our Lincoln Park clinic. Results arrive within 5 to 7 business days through our lab partner. Your provider then schedules a review consultation to walk through all 22 panels in context, identify cross-domain patterns, flag early risk signals, and connect findings to a specific treatment or optimization strategy.
Most clinics run a lipid panel and call it cardiovascular screening. We run Apo-B, Lp(a), and homocysteine because those are the markers that actually predict events. Most panels skip ESR. We include it alongside hs-CRP for a dual inflammation read. The Executive Longevity Panel reflects how longevity medicine actually works: measure what matters, not just what insurance will cover.
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An 8-to-12-hour fast is required before your appointment. Water and black coffee are fine. Skip supplements the morning of your draw, particularly biotin and B vitamins, which can interfere with certain hormone and thyroid assays. The blood draw is performed at our clinic at 2117 N Halsted St in Lincoln Park, Chicago, and takes approximately 10 minutes. For patients outside Chicago or with scheduling constraints, we can order your draw at a lab center near you.
The Executive Longevity Panel covers everything in the Elite Performance Optimization Panel (19 panels across hormones, thyroid, metabolic, inflammatory, nutritional, and hematologic domains) plus three markers that elevate this panel into longevity-grade diagnostics.
Apolipoprotein Evaluation (Apo-A-1, Apo-B, Lp(a)): This is the centerpiece addition. Standard lipid panels measure LDL cholesterol, which tells you how much cholesterol is in your LDL particles. Apo-B tells you how many atherogenic particles you have, which is a fundamentally better predictor of cardiovascular risk. Two patients with identical LDL-C can have dramatically different Apo-B levels, and it is the particle count that drives plaque formation. Lp(a) is a genetically determined lipoprotein variant that increases cardiovascular risk independently of all other lipid markers. You cannot lower Lp(a) through diet or exercise. If it is elevated, the clinical conversation changes: your provider may recommend earlier statin consideration, PCSK9 inhibitor evaluation, or more aggressive lifestyle modification on the factors you can control. Most physicians never test Lp(a). Most patients have no idea where they stand. This panel changes that.
Homocysteine: An amino acid byproduct of methionine metabolism. Elevated homocysteine is an independent risk factor for cardiovascular disease, stroke, and cognitive decline. It also reflects B-vitamin metabolism (B12, folate, B6), which means it connects cardiovascular risk assessment to the nutritional picture this panel already captures. A patient with elevated homocysteine and low B12 has a clear, actionable finding. A patient with elevated homocysteine and normal B-vitamins needs a different investigation. Either way, you cannot act on what you have not measured.
Sedimentation Rate (ESR): A second inflammatory marker alongside hs-CRP. CRP is an acute-phase reactant that rises quickly with inflammation. ESR moves more slowly and reflects longer-term inflammatory trends. Running both gives your provider a dual-axis view: elevated CRP with normal ESR suggests acute or recent inflammation, while both elevated together suggests a chronic inflammatory process. This distinction changes clinical decisions.
TSH, Free T3, Free T4, Total T4, Thyroid Peroxidase Antibodies: The complete thyroid picture, including the autoimmune marker (TPO) that most standard panels omit. Low Free T3 with normal TSH is one of the most common missed findings in patients with fatigue, weight gain, and brain fog. Elevated TPO indicates Hashimoto's thyroiditis before overt hypothyroidism develops.
Testosterone, Free & Total w/ SHBG: Bioavailable testosterone assessment. SHBG context is essential for clinical decisions about TRT, Enclomiphene, or Kindling (Kisspeptin).
Estradiol (E2): Relevant for men (aromatase activity monitoring) and women (cycle health, menopausal status, HRT decisions).
FSH & LH: Pituitary hormones that drive gonadal function. Distinguishes primary from secondary hypogonadism and evaluates HPG axis integrity.
Cortisol + DHEA-Sulfate: Adrenal stress axis assessment. Chronic cortisol elevation or DHEA-S depletion impacts every other system this panel measures.
CMP + Fasting Insulin + Lipid Panel: Organ function, insulin sensitivity (the earliest metabolic dysfunction marker), and standard cardiovascular lipids.
Vitamin B12, Vitamin D, Magnesium, Iron + TIBC: The four nutritional markers most commonly deficient and most commonly missed in standard bloodwork. Each connects directly to energy, immune function, hormone production, and cognitive performance.
CBC with Differential + hs-CRP: Hematologic baseline and high-sensitivity inflammatory marker.
Results are typically available within 5 to 7 business days through Access Medical Labs. Your provider schedules a review consultation (in-person at our Lincoln Park clinic or via telehealth) to walk through all 22 panels. The Executive Longevity Panel review is more than a line-by-line readout. Your provider looks for cross-domain patterns: elevated Apo-B combined with high fasting insulin and chronic inflammation tells a different story than elevated Apo-B in isolation. Low Free T3 combined with high cortisol and depleted magnesium points to a stress-thyroid interaction that neither marker explains on its own. The goal is to connect your results to a specific clinical plan, whether that involves peptide therapy, hormone optimization, cardiovascular risk management, targeted supplementation, IV therapy, or a referral to a specialist when the data warrants it.
Many longevity-focused patients re-run this panel annually or semi-annually to track changes over time. Your first panel establishes the baseline. Every subsequent draw quantifies the impact of the interventions you and your provider have implemented.
Get the longevity-grade data your annual physical will never provide.
Book the Executive Longevity Panel at Better Med Spa in Lincoln Park. 22 panels. One draw. A provider review that connects your results to a long-term plan.
22 panels including Apo-B, Lp(a), homocysteine, full hormones, and complete thyroid. The longevity panel for patients who want to manage risk before it becomes disease. $575 at Better Med Spa.
Standard bloodwork is designed to detect disease after it has arrived. Your annual physical checks enough markers to flag diabetes once your glucose is abnormal, identify thyroid failure once your TSH is out of range, and catch cardiovascular risk once your LDL is elevated. By the time those markers move, the underlying dysfunction has often been developing for years.
Longevity medicine operates on a different timeline. It asks: what can we measure today that predicts what happens in 10, 20, or 30 years? And what can we do about it now, while the window for intervention is still wide open? The Executive Longevity Panel at Better Med Spa in Lincoln Park, Chicago, is built around that question. It covers 22 panels across seven clinical domains, including three advanced cardiovascular risk markers (Apo-B, Lp(a), and homocysteine) that longevity physicians consider essential and that standard medicine almost never orders.
This is not a panel for patients who feel sick and want a diagnosis. It is a panel for patients who feel fine and want to stay that way. It is for the patient who has read Outlive, who follows the longevity research, who understands that the time to manage cardiovascular risk is 20 years before the event, not after the first stent. And it is for the patient who wants a provider at Better Med Spa who will actually interpret the data and connect it to a plan.
The standard lipid panel measures how much cholesterol is carried by your LDL particles. Apolipoprotein B measures how many atherogenic particles you have. This distinction matters because cardiovascular events are driven by particle count, not cholesterol content. Two patients with LDL-C of 100 mg/dL can have very different Apo-B levels, and it is the patient with more particles who carries higher risk. Longevity physicians increasingly treat Apo-B as the primary metric for cardiovascular risk management rather than LDL-C, because it captures the full picture of all atherogenic lipoproteins (LDL, VLDL, IDL, and Lp(a)) in a single number.
Lipoprotein(a), or Lp(a), deserves its own discussion. It is a genetically determined lipoprotein variant that roughly 20% of the population carries at elevated levels. Elevated Lp(a) increases cardiovascular risk independently of every other lipid marker on a standard panel. You cannot lower Lp(a) through diet, exercise, or statin therapy. It is essentially a genetic cardiovascular risk factor that most people carry unknowingly because most doctors have never ordered the test. Knowing your Lp(a) level changes the conversation: if it is elevated, your provider can adjust the aggressiveness of every other risk factor you can control (blood pressure, metabolic health, inflammation, Apo-B) to compensate for the one you cannot. If it is normal, you have one fewer variable to worry about. Either way, the information is actionable, and not knowing it is a gap that longevity medicine considers unacceptable.
Homocysteine is an amino acid byproduct of methionine metabolism that, when elevated, is an independent risk factor for cardiovascular disease, stroke, venous thromboembolism, and cognitive decline including dementia. It sits at the intersection of cardiovascular and neurological risk, which makes it uniquely valuable in a longevity context where the goal is to protect both the heart and the brain over decades.
Homocysteine also reflects B-vitamin metabolism. Your body uses B12, folate, and B6 to recycle homocysteine back into methionine or convert it to cysteine. When those vitamins are deficient, homocysteine accumulates. This means an elevated homocysteine finding connects directly to the nutritional markers already on this panel (Vitamin B12 and the CMP's protein markers), creating a cross-domain pattern your provider can act on. In many cases, elevated homocysteine is correctable with targeted B-vitamin supplementation or methylation support, making it one of the most actionable findings on the entire panel.
The Executive Longevity Panel includes two inflammatory markers: hs-CRP and ESR. Most panels include one or neither. The reason for including both is that they reflect different inflammatory dynamics. CRP is an acute-phase reactant produced by the liver in response to IL-6 signaling. It rises quickly (hours to days) and can be elevated by acute infection, tissue injury, or chronic low-grade inflammation. ESR measures how fast red blood cells settle in a tube over one hour, which is influenced by inflammatory proteins (especially fibrinogen and immunoglobulins) that accumulate more gradually. Running both lets your provider distinguish between acute inflammatory events and chronic inflammatory processes, which informs whether the appropriate response is a short-term intervention or a sustained lifestyle and treatment strategy.
Patients with a family history of cardiovascular disease. If a parent or sibling experienced a heart attack, stroke, or required cardiovascular intervention before age 65, your risk profile is different from the general population. Standard lipid panels do not capture that difference. Apo-B, Lp(a), and homocysteine do. Knowing these numbers early (ideally in your 30s or 40s) gives you and your provider decades of runway to manage modifiable risk factors before they compound.
Longevity-minded patients in their 30s through 60s. The executive and professional patient base across Lincoln Park, Gold Coast, River North, Lakeview, and Bucktown who reads the research, understands compound risk, and wants to manage their health trajectory proactively. These patients often already have a peptide protocol or hormone optimization plan in place and want the diagnostic tier that matches their level of investment.
Patients already on the Better Med Spa peptide or hormone menu. If you are running Sentinel (Thymosin Alpha-1), Synapse (Dihexa), Sleep & Sculpt, or any other protocol, the Executive Longevity Panel is the annual or semi-annual diagnostic check-in that validates your progress and catches emerging patterns before they become problems. It is the difference between "I feel better" and "my markers prove I am better."
Patients upgrading from the Elite Performance Optimization Panel. If you ran the Elite Performance panel and want the advanced cardiovascular layer on your next draw, the Executive Longevity Panel adds Apo-B, Lp(a), homocysteine, and ESR. The $150 step up from $425 to $575 buys you the markers that longevity physicians consider non-negotiable, particularly if cardiovascular risk is in your family history or if you are over 40.
Patients whose doctors told them their cholesterol is "fine." LDL-C within range does not mean your cardiovascular risk is low. Apo-B can be elevated with normal LDL. Lp(a) can be elevated with a perfect lipid panel. Homocysteine can be high with normal cholesterol. Standard bloodwork provides false reassurance by measuring the wrong things. The Executive Longevity Panel measures the right things.
Markers: 22 panels 7 clinical domains
Includes: Blood draw at 2117 N Halsted St (or mobile draw order), all 22 panels processed through Access Medical Labs, and a provider review consultation (in-person or telehealth)
Key additions vs. Elite Performance Panel: Apolipoprotein Evaluation (Apo-A-1, Apo-B, Lp(a)), Homocysteine, Sedimentation Rate (ESR)
Fasting required: 8-12 hours. Water and black coffee permitted.
Results timeline: 5-7 business days
Available to: In-person patients (Lincoln Park) and telehealth patients (Illinois statewide)
Pricing is all-inclusive. No separate draw fee, no separate consultation fee. The $575 covers every marker, the draw, and a provider review where your results are interpreted in context and connected to a specific clinical plan.
Markers: 6 (CBC, CMP, TSH, HbA1c, Lipid Panel, Vitamin D)
Best for: First-time screening, weight loss candidacy, general metabolic baseline
Markers: 13 panels covering hormones, full thyroid with TPO, and metabolic markers
Best for: Hormone-focused evaluation, thyroid deep dive, TRT candidacy
Markers: 19 across 6 clinical domains
Best for: Pre-protocol assessment, performance optimization, patients who want comprehensive hormonal + metabolic + nutritional data
Markers: 22 panels 7 clinical domains
Best for: Longevity-focused patients, cardiovascular risk assessment, annual longevity check-in, patients with family history of heart disease
Key differentiator: Apo-B, Lp(a), homocysteine, and dual inflammatory markers (hs-CRP + ESR)
The diagnostic menu is designed as a clear ladder. Start with the Advanced Wellness Baseline if you are new to data-driven wellness. Step up to the Elite Performance Panel when you are ready for the complete hormonal, metabolic, and nutritional picture. Run the Executive Longevity Panel when you want the cardiovascular and longevity layer that separates proactive health management from reactive medicine. Your provider can help you determine which tier fits your goals and budget during your consultation.
Yes. An 8-to-12-hour fast is required for accurate fasting insulin and lipid results. Water and black coffee are fine. Skip supplements the morning of your draw.
The Executive Longevity Panel is a cash-pay service. Insurance-based lab ordering frequently limits which markers a provider can request, and the advanced cardiovascular markers (Apo-B, Lp(a), homocysteine) are precisely the ones that insurance often does not cover for asymptomatic screening. At $575 all-inclusive, you get every marker without insurance restrictions determining what gets tested.
If cardiovascular health is a priority, if you have a family history of heart disease or stroke, or if you are over 40 and want the full longevity picture, yes. The Apo-B and Lp(a) data alone are worth the upgrade because they reveal risk that no other marker on the Elite Performance Panel can detect. If your primary concern is hormonal or metabolic and cardiovascular risk is not a focus area, the Elite Performance Panel remains a strong choice.
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