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The Total Wellness Intelligence Panel is our deepest diagnostic blood draw: 23 panels that go beyond hormones and metabolic health into the functional terrain most providers never explore. This panel includes trace mineral assessment (iodine, selenium, copper, zinc), functional B-vitamin and methylation markers (B6, B12 with folate, methylmalonic acid), advanced cardiovascular risk (Apo-B, Lp(a), homocysteine), comprehensive thyroid, sex hormones with SHBG and progesterone, iron stores (ferritin + total iron), and long-range metabolic markers (HbA1c, fasting insulin). It is designed for the patient who does not want gaps in the data and whose provider needs the full picture to build a protocol that addresses root causes, not just symptoms.
This panel targets root-cause physiology across eight domains: comprehensive thyroid, sex hormones with progesterone, metabolic and insulin health, advanced cardiovascular risk, functional B-vitamin and methylation status, trace mineral balance (iodine, selenium, copper, zinc), iron storage, and systemic inflammation. It is built for the patient who wants to understand why their body functions the way it does.
An 8-to-12-hour fast is required. The blood draw takes about 10 minutes at our Lincoln Park clinic. Results arrive within 5 to 10 business days depending on trace metal and specialty assays. Your provider then schedules an extended review consultation to interpret all 23 panels in context, identify root-cause patterns across domains, and build a clinical plan around what the data reveals.
The tests on this panel are ones most providers have never ordered: iodine, RBC selenium, copper, methylmalonic acid, B6. These are the markers that explain why your thyroid medication isn't working, why your energy hasn't improved despite normal labs, or why your homocysteine stays elevated. We run them because root-cause answers require root-cause data. Your provider reviews every result and builds a plan.
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An 8-to-12-hour fast is required before your appointment. Water and black coffee are fine. Skip supplements the morning of your draw. This is especially important for this panel because biotin, B vitamins, zinc, and iron supplements can directly interfere with several assays. If you are on thyroid medication, take it as prescribed unless your provider advises otherwise. The blood draw is performed at our clinic at 2117 N Halsted St in Lincoln Park, Chicago, and takes approximately 10 minutes. For patients outside Chicago, we can order your draw at a lab center near you.
The Total Wellness Intelligence Panel is organized around a root-cause framework. Rather than simply checking whether your numbers are in range, this panel is designed to reveal the upstream factors that drive dysfunction across your thyroid, hormones, metabolism, cardiovascular system, and nervous system.
These are the markers that make this panel fundamentally different from everything else on the Better Med Spa diagnostic menu. Most panels never touch them. They are expensive to run and require specialty assays. They are also some of the most clinically actionable findings a provider can uncover.
Iodine/Plasma Trace Metal: Iodine is the raw material your thyroid uses to produce T4 and T3. Without adequate iodine, no amount of thyroid medication or thyroid-stimulating peptide will produce optimal results. Iodine deficiency is more common than most physicians realize, particularly in patients who avoid iodized salt or follow restrictive diets. This is the marker that explains why some patients with "normal" thyroid panels still have thyroid symptoms.
RBC Selenium: Selenium is required for the enzyme (deiodinase) that converts T4 into the active T3 hormone. It is also essential for glutathione peroxidase, your body's primary antioxidant defense system. RBC selenium measures long-term selenium status inside red blood cells, which is more clinically meaningful than a serum snapshot. Low selenium combined with suboptimal Free T3 is one of the most common and most correctable root-cause patterns in thyroid patients.
Copper/Plasma Trace Metal: Copper is essential in small amounts but problematic in excess. The copper-to-zinc ratio is a functional medicine marker for oxidative stress, hormonal disruption, and inflammation. Elevated copper relative to zinc is associated with estrogen dominance, anxiety, and immune dysfunction. This marker gives context to your hormonal and inflammatory findings.
Zinc: Involved in over 300 enzymatic reactions including testosterone production, immune function, thyroid conversion, and wound healing. Zinc deficiency is widespread and almost never tested in standard bloodwork. It also directly impacts the copper-zinc ratio, making it essential context for the copper result.
Magnesium: Involved in over 300 enzymatic reactions including muscle function, sleep quality, stress response, and blood sugar regulation. Frequently deficient, rarely tested.
Standard B12 testing catches severe deficiency but misses functional depletion. This panel goes deeper.
Methylmalonic Acid (MMA): The gold-standard functional marker for B12 status at the cellular level. Serum B12 can be within normal range while MMA is elevated, indicating that your cells are not getting enough B12 to run methylation and energy pathways properly. If you have fatigue, cognitive fog, or neuropathy with "normal" B12, MMA is the marker that catches what serum B12 misses.
Vitamin B6: Critical for neurotransmitter synthesis (serotonin, dopamine, GABA), homocysteine metabolism, and immune function. B6 deficiency contributes to mood disorders, neuropathy, and elevated homocysteine. It is one of the most functionally important and least commonly tested vitamins.
Vitamin B12 & Folate: Measured together because they work in tandem for methylation, red blood cell production, and homocysteine recycling. Combined with MMA, this gives your provider a three-dimensional view of B-vitamin status rather than a single serum number.
Apolipoprotein Evaluation (Apo-A-1, Apo-B, Lp(a)): Apo-B measures atherogenic particle count (a superior predictor vs. LDL-C). Lp(a) is a genetically determined cardiovascular risk factor that cannot be lowered through lifestyle. Apo-A-1 measures the protective HDL-associated protein. Together, they provide the cardiovascular risk picture that a standard lipid panel cannot.
Homocysteine: Cardiovascular and neurological risk marker. Elevated levels linked to heart disease, stroke, and cognitive decline. Connects directly to the B-vitamin and methylation markers on this panel: B12, folate, and B6 are the cofactors your body uses to keep homocysteine in check. An elevated homocysteine with the B-vitamin data from this panel gives your provider a clear, actionable root-cause pathway.
Thyroid Panel Comprehensive: A broad thyroid assessment covering TSH, Free T3, Free T4, Total T4, T3 Uptake, and additional thyroid markers in a single comprehensive panel. When interpreted alongside the trace minerals (iodine, selenium) and micronutrients (zinc, B12) on this panel, your provider can see not just what your thyroid is producing but why it may be underperforming and what is needed to support it at the root cause level.
Testosterone, Free & Total w/ SHBG: Bioavailable testosterone assessment with binding protein context.
Estradiol (E2): Primary estrogen. Interpreted alongside copper and zinc for hormonal balance context.
Progesterone: Adds the reproductive hormone most panels omit. Essential for menstrual cycle assessment in women and hormonal balance evaluation in both sexes. Low progesterone relative to estradiol is a common finding in patients with anxiety, sleep disruption, and cycle irregularity.
CMP + Fasting Insulin + HbA1c: The metabolic triad. CMP covers organ function. Fasting insulin catches insulin resistance years before glucose becomes abnormal. HbA1c provides a 90-day blood sugar average that a single fasting glucose cannot capture. Together, they give a complete metabolic trajectory rather than a single-point snapshot.
Ferritin + Iron, Total: Ferritin measures iron storage, which is more clinically useful than serum iron alone. A patient can have normal serum iron with depleted ferritin, which means their reserves are empty even though today's circulating iron looks fine. This pattern is one of the most common causes of unexplained fatigue, especially in women.
DHEA-Sulfate: Adrenal precursor to sex hormones. Reflects adrenal reserve and chronic stress burden.
hs-CRP: High-sensitivity inflammatory marker for cardiovascular risk and systemic inflammation.
CBC with Differential: Hematologic baseline. Red blood cells, white blood cells, hemoglobin, hematocrit, platelets with white cell differential.
Vitamin D, 25-OH Total: Vitamin D status. Impacts immune function, bone health, mood, hormone production, and thyroid function. Deficiency is widespread in Chicago.
Results for standard markers arrive within 5 to 7 business days. Trace metal and specialty assays (iodine, copper, selenium, MMA, B6) may take up to 10 business days depending on the lab run schedule. Once all results are in, your provider schedules an extended review consultation (in-person at our Lincoln Park clinic or via telehealth). This review is longer and more detailed than the standard panel reviews because the Total Wellness Intelligence Panel generates cross-domain patterns that require careful interpretation.
For example: elevated homocysteine + low B6 + low B12/folate + elevated MMA points to a methylation and B-vitamin processing issue that connects cardiovascular risk to neurological symptoms to energy production. Suboptimal Free T3 + low iodine + low selenium + elevated TPO (if present on a prior panel) tells a thyroid story that no single marker could tell alone. Elevated copper + low zinc + high estradiol maps a hormonal and oxidative stress pattern that informs both supplementation and treatment strategy. Your provider reads these patterns and connects them to a specific clinical plan: targeted supplementation, peptide therapy, hormone optimization, IV therapy, dietary guidance, or a referral when the data points beyond our scope.
Get the deepest diagnostic picture available at Better Med Spa.
Book the Total Wellness Intelligence Panel in Lincoln Park. 23 panels. Trace minerals. Methylation. Cardiovascular. Hormones. The root-cause data that changes the conversation.
23 panels including trace minerals, methylation, Apo-B, Lp(a), and full hormones. The functional medicine panel for patients who want root-cause answers. $1,000 at Better Med Spa.
Most blood panels measure what is happening in your body. The Total Wellness Intelligence Panel measures why. The distinction is not semantic. A standard thyroid panel shows your TSH and maybe Free T4. It does not show that your iodine is depleted (so your thyroid lacks raw material), your selenium is low (so you cannot convert T4 to active T3), and your zinc is deficient (which further impairs thyroid hormone receptor sensitivity). Those three findings change the clinical conversation entirely. Instead of increasing thyroid medication, your provider can address the mineral deficiencies that are driving the dysfunction in the first place.
The same root-cause logic applies across every domain this panel covers. Elevated homocysteine on a standard panel gets flagged as a cardiovascular risk factor. Elevated homocysteine on this panel gets connected to low B6 and elevated methylmalonic acid, which tells your provider that the methylation cycle is impaired at a specific enzymatic step and can be corrected with targeted B-vitamin support. Low energy with normal CBC gets dismissed by most physicians. Low energy with depleted ferritin, suboptimal B12 (confirmed by elevated MMA), and low magnesium gives your provider three actionable deficiencies that explain the symptom.
At Better Med Spa in Lincoln Park, Chicago, the Total Wellness Intelligence Panel is our deepest diagnostic offering. It covers 23 panels across eight clinical domains and includes trace mineral and functional testing that most providers have never ordered, let alone interpreted. This panel is not for everyone. It is for the patient who has already tried the surface-level approach and wants to go deeper.
Better Med Spa's diagnostic menu is built as a progression. Each tier adds clinical depth for patients who need it:
The Advanced Wellness Baseline Test ($200) is the entry point: basic metabolic, hematologic, and thyroid screening for patients who want a starting snapshot. The Elite Performance Optimization Panel ($425) adds full thyroid with antibodies, complete sex hormones with SHBG, adrenal markers, fasting insulin, inflammatory markers, and nutritional status. The Executive Longevity Panel ($575) layers on advanced cardiovascular risk with Apo-B, Lp(a), homocysteine, and dual inflammatory markers.
The Total Wellness Intelligence Panel goes in a different direction. Rather than adding more markers to the same domains, it shifts into functional and integrative diagnostics: the trace minerals, methylation markers, and specialty assays that explain why your other labs look the way they do. It includes iodine (thyroid raw material), RBC selenium (thyroid conversion enzyme), copper (oxidative stress and hormonal balance), methylmalonic acid (functional B12 at the cellular level), vitamin B6 (neurotransmitter synthesis and homocysteine metabolism), ferritin (iron storage beyond serum iron), HbA1c (90-day metabolic trend), and progesterone (the missing reproductive hormone). These are not incremental additions. They are the markers that move the conversation from "what is your number" to "why is your number what it is."
Patients whose labs have always come back "normal" but who still don't feel right. This is the core patient for this panel. If your TSH is in range but you are fatigued, gaining weight, losing hair, and struggling to think clearly, the problem may be that nobody has checked your iodine, selenium, ferritin, or methylmalonic acid. The Total Wellness Intelligence Panel tests what standard bloodwork does not, which is where the answers usually are.
Thyroid patients who want the complete picture. If you are on thyroid medication and it is not working as well as expected, or if you have been told your thyroid is "borderline" and to wait and see, this panel provides the upstream context. Iodine, selenium, zinc, and copper all directly impact thyroid hormone production and conversion. Addressing those deficiencies can change the thyroid picture more effectively than adjusting medication dose.
Patients with persistent fatigue, brain fog, or mood issues. The methylation and B-vitamin markers on this panel (MMA, B6, B12 with folate) are the functional diagnostics that connect neurological symptoms to specific biochemical pathways. A patient with brain fog and elevated MMA has a cellular B12 deficiency that serum B12 alone would miss. A patient with anxiety and an elevated copper-zinc ratio has an oxidative stress pattern that mood questionnaires cannot detect.
Patients building a comprehensive longevity and optimization protocol. If you are already running peptides, hormone therapy, IV therapy, and targeted supplementation through Better Med Spa, the Total Wellness Intelligence Panel is the annual or semi-annual deep dive that validates your entire stack. It catches the trace mineral and methylation gaps that accumulate subtly over time and that lower-tier panels are not designed to find.
Women navigating hormonal complexity. The addition of progesterone, comprehensive thyroid, ferritin, and the copper-zinc ratio makes this panel particularly valuable for women in Lincoln Park, Lakeview, Old Town, Gold Coast, and Bucktown managing cycle irregularity, perimenopausal symptoms, postpartum recovery, or unexplained weight and mood changes. The progesterone-to-estradiol relationship, interpreted alongside copper, zinc, and thyroid function, reveals hormonal patterns that a standard hormone panel cannot capture.
Patients referred from functional medicine or integrative health backgrounds. If you have worked with a naturopath, functional medicine practitioner, or integrative physician and are looking for a provider in Chicago who runs these same markers within a med spa setting, the Total Wellness Intelligence Panel covers the functional terrain you expect. Better Med Spa bridges the gap between integrative diagnostics and the treatment modalities (peptide therapy, IV therapy, hormone optimization) that turn functional data into clinical action.
Panels: 23 across 8 clinical domains
Key differentiators: Iodine, RBC Selenium, Copper, Zinc, Methylmalonic Acid, Vitamin B6, B12 & Folate, Ferritin, HbA1c, Progesterone, Comprehensive Thyroid Panel, Apolipoprotein Evaluation
Includes: Blood draw at 2117 N Halsted St (or mobile draw order), all 23 panels, and an extended provider review consultation (in-person or telehealth)
Fasting required: 8-12 hours. Water and black coffee permitted.
Results timeline: 5-10 business days (trace metal and specialty assays may require additional processing time)
Available to: In-person patients (Lincoln Park) and telehealth patients (Illinois statewide)
Pricing is all-inclusive. No separate draw fee. No separate consultation fee. The $1,000 covers every marker, the draw, and an extended provider review where your results are interpreted across all eight domains and connected to a specific clinical plan. The extended review for this panel is longer than the standard panel review because the cross-domain pattern analysis (trace minerals interacting with thyroid function, methylation interacting with cardiovascular risk, copper-zinc ratio interacting with hormonal balance) requires more time and clinical attention.
Markers: 6 | Focus: Basic metabolic, hematologic, thyroid screening
Best for: First-time patients, weight loss candidacy, general health snapshot
Markers: 13 | Focus: Hormones, full thyroid, metabolic health
Best for: Hormone evaluation, TRT candidacy, thyroid deep dive
Markers: 19 | Focus: Hormones + thyroid + metabolic + nutritional + inflammatory
Best for: Pre-protocol baseline, performance patients, comprehensive hormonal and metabolic picture
Markers: 22 | Focus: Everything in Elite + advanced cardiovascular (Apo-B, Lp(a), homocysteine, ESR)
Best for: Longevity patients, cardiovascular risk assessment, family history of heart disease
Panels: 23 | Focus: Functional diagnostics: trace minerals, methylation, root-cause thyroid, advanced cardiovascular, hormones with progesterone
Best for: Root-cause investigation, persistent symptoms with "normal" labs, thyroid optimization, functional medicine patients, comprehensive longevity protocol validation
Each tier serves a different patient at a different stage of their health journey. If you are new to data-driven wellness, start with the Baseline. If you want performance-grade data, run the Elite Performance panel. If cardiovascular risk is your focus, the Executive Longevity panel adds Apo-B and Lp(a). If you want to understand why your body functions the way it does at the deepest level available, the Total Wellness Intelligence Panel is the one to run. Your provider can help you determine which tier fits your goals during your consultation.
Both. Every marker is relevant for both sexes. The inclusion of progesterone and the copper-zinc ratio makes this panel particularly valuable for women navigating hormonal complexity, but the trace mineral, methylation, and cardiovascular markers are equally relevant for men. Your provider contextualizes every result based on your sex, age, symptoms, and goals.
Standard markers return within 5 to 7 business days. Trace metal and specialty assays (iodine, copper, selenium, MMA, B6) may take up to 10 business days depending on lab processing schedules. Your provider waits for all results before scheduling the review consultation so everything can be interpreted together.
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